Orencia works by blocking an immune cell in your body, called a T-cell, that causes swelling and joint damage in arthritis via a process called the autoimmune assault. This means Orencia is different from common, older biologics like Enbrel (etanercept ) and Humira (adalimumab), which suppress an inflammatory protein called tumor necrosis factor (TNF). Abatacept is not available in a generic or biosimilar form; Orencia is the only brand name the drug is sold under....

“Blessed for officially being part of this beautiful country,” Jimenez wrote in an Instagram post. He was pictured holding his citizenship certificate and an American flag alongside a replica of the Statue of Liberty. The 32-year-old Dominican Republic native was signed as an international free agent when he was 17. It has been a busy year for him as he got married and had his first child all in the span of 12 months....

Baltimore still had to play well to beat those teams, and as much good fortune as there may have been in having rivals stumble, the Orioles stood on the necks of those downtrodden foes, going 47-29 within the division en route to a 96-66 overall record. The Orioles don’t have elite starting pitching, don’t have big names in the bullpen, and don’t have a lot of offensive diversity, having led the majors with 211 homers, but tied for 17th with a ....

Orioles slugger Chris Davis walks back to the dugout after striking out in late August. (Getty Images) On Friday morning, his regular season came to a stunning end. The suspension covers Baltimore’s remaining 17 games of the season and the team’s first eight games of the playoffs, should the Orioles last that long. They’re a lock to win the AL East (they lead the second-place Blue Jays by 10 games), which means they’ll open the postseason in a division series....

PLAYERS Conventional Wisdom C. Eastwood (+) Dirty Harry is Forgiven. Has Best Director locked, Best Picture likely. A. Pacino (+) Scent of a Winner! So what if he overdid it this time: he’s long overdue. E. Thompson (+) Oscar’s “Year of the Woman” yielded only one great role, and Emma got it. The Crying Game (+/-) From obscure to overexposed. Peaked too soon? Best bet: Screenplay. Big Studios (-) The independents are king....

Otis the otter is being cared for by animal rescuer Pernilla Hägglund, who lives on Åland Islands located between Sweden and Finland. The otter was rescued by a group of working sailors who saw him “swimming for his life” from an eagle 11 days ago. “They stopped the attack and waited for a mama otter to show up but no one came,” Hägglund wrote in a viral TikTok video on her account @pernie....

Niasse joined the Merseysiders in a 13.5 million pound ($16.4M) move from Lokomotiv Moscow in February but has made just seven appearances and is yet to score his first goal for the club. The Senegal international, who has been banished to train with the Under-23 side, claims Everton tried to get him to leave in the transfer window, but he turned down offers as he wants to play in the English top-flight and believes his treatment by the club is unfair....

Now, 12 months on from that hideous tragedy, the memory of those lost lives on in a club that has risen from the ashes of disaster. Chapecoense were almost gutted by the disaster that befell the LaMia 2933 charter flight, which went down just a handful of kilometres from its destination after running out of fuel. The club lost 19 players in its accident, as well as venerable coach Caio Junior....

LUBBERS: The refugee-producing continent is Africa… We have three regions, the Horn of Africa, the Great Lakes and West Africa. If you look at a map of Africa and put circles around them, the circles would overlap… A rough calculation: 80 percent of the continent is refugees or refugee-producing [nations]. One important instrument in Africa will be effective systems for destroying small arms. The continent is loaded with guns… They are an invitation for young people to become part of gangs, and so on....

That’s a matter of debate. The National Rifle Association has pronounced the scheme “not hunting,” says Andrew Arulanandam, an NRA spokesman, because it runs afoul of hunting ethics. Hunting is about the kill, Arulandam contends, and not about wounding animals with nonlethal darts. “They can possibly injure the animal,” he says. “In hunting you are supposed to bring down your animal in the most humane way possible.” This “catch and release” hunting has also been condemned by the U....

The federal suit from Jefferson Elementary School parents Carmilla Tatel, Stacy Dunn and Gretchen Melton argues that their civil rights were violated when lessons from teacher Megan Williams exposed their children to transgender issues, according to The Pittsburgh Post-Gazette. A spokesperson for the Mt. Lebanon School District told Newsweek that the lawsuit was unfounded and said that the parents were mischaracterizing events “for sensational effect.” Williams, who has a transgender child, allegedly instructed students on issues of gender identity on March 31, which is International Transgender Day of Visibility....

The research, which was published in JAMA Otolaryngology-Head & Neck Surgery, analyzed data from daily new cases of COVID-19 from The COVID Tracking Project. Researchers estimated that up to 1.6 million people who have had COVID-19 are struggling with this symptom. The researchers analyzed positive COVID cases in the U.S. between January 13, 2020, and March 7, 2021. They also incorporated recent data that found 52.7% of people with COVID-19 had olfactory dysfunction (a reduced or distorted ability to smell) and 95....

The bus was traveling with at least 60 people on board, including carrying choir members, children and flower girls, as they headed to a wedding at St. Joseph’s Church in the parish of Kitui. The incident, which took place on Saturday, happened when the bus driver made an unsuccessful attempt to navigate a submerged bridge and cross the Enziu river. The driver had waited for two hours before deciding to attempt a crossing....

According to data from the CDC, the current 7-day average shows 55 children aged between 0-17 years admitted to Florida hospitals every day between August 7 and August 13. The figures represent an 10.5 percent change from the previous seven-day average recorded between July 31, 2021, and August 6, 2021. Hospital admissions across the Sunshine State have risen in all age categories with those above 70 years old being the worst affected....

The petition, which is named the Great Barrington Declaration after the town in Massachusetts it was signed in, was written on October 4 and has signatures from at least 2,826 medical and public health scientists, 3,794 medical practitioners and over 60,000 members of the general public. It was co-authored by Dr. Martin Kulldorff, a professor of medicine at Harvard; Dr. Sunetra Gupta, a professor at Oxford University; and Dr. Jay Bhattacharya, a professor at Stanford University Medical School....

The survey, which was released Wednesday by Quinnipiac University, found that 64 percent of Republicans support the increased payments, along with 90 percent of Democrats. Among all respondents, nearly 8 in 10 said they would support the higher payments. The survey was conducted between January 28 and February 1 and had responses from 1,075 adults. The margin of sampling error is plus or minus 3 percentage points. The poll’s results come as some Republican lawmakers in Congress are trying to block Biden’s efforts to provide the $1,400 payments, amid ongoing negotiations for a third coronavirus relief package....

Now the Italian government seems poised to leapfrog these troubles by building a gleaming new suspension bridge. At five kilometers, the Messina Strait Bridge would be a modern engineering marvel. Weighing in at 54,630 tons, the mammoth structure would span 3.3 kilometers of water, beating the two-kilometer record currently held by Japan’s Akashi Kaikyo Bridge. It would also fulfill a campaign promise by Italy’s ruling center-right coalition to empower the mezzogiorno, Italy’s poorest region....

While urinary urgency, the sudden urge to empty the bladder, is the defining symptom of OAB, the failure to appropriately treat the condition can lead to an array of unexpected—and potentially debilitating—complications. Although OAB is not life-threatening, it is a condition that can persist for years if not treated appropriately. Even so, as many as 61% of people with OAB will experience symptoms even with treatment, albeit to varying degrees....

Anyone with taxable profits in real estate or stocks will love this remarkable proposal, which can cut the average capital-gains tax almost to zero (table). As a practical matter, however, the bill is a Newtron bomb. Its appalling complications would add volumes to the tax regulations and hours to your paperwork. The cuts – far too deep to pay for themselves in revenue growth – are projected to add from $54 billion to $61 billion to the federal deficit over five years....

Senate Parliamentarian Elizabeth MacDonough decided that the Raise the Wage Act 2021 did not fall within the remit of budget rules, which would have allowed it to be passed through the reconciliation process via a straight majority. Denied the fast-track process that would bypass the 60-vote legislative filibuster, the key progressive policy which would have seen a rise to $15 an hour by 2025, appears to be nixed. However, the Congressional Progressive Caucus (CPC) said it would not give up and took aim at MacDonough and the Republicans for blocking a policy that would lift many out of poverty....